פרופ' חיים עינת

Prof. Haim Einat

מוסד עיקרי

המכללה האקדמית ת"א יפו

The Academic College of Tel Aviv Yaffo

דוא״ל

haimh@mta.ac.il

קורות חייםCV

דיסציפלינות ראשיותMain Disciplines

Animal Science, Behavioural sciences, Psychiatry, Psychobiology

דיסציפלינות משניותSecondary Disciplines

Animal Behavior

תחומי מחקר / מילות מפתחKeywords

Affective disorders, Animal models, Bipolar disorder, Circadian rhythms, Depression

פרסומים ויצירות עיקריים / עדכנייםMain / Recent Publications

Eva-Maria Tsapakis, Konstantinos N. Fountoulakis, Stefania Kanioura, Haim Einat, Significant contribution of chronotype to emotional well-being in chronic psychiatric outpatients in Greece, Neuroscience Applied, Volume 3, 2024, 103940
Bilu, C., Butensky, N., Malamud, A.R. et al. Effects of photoperiod and food on glucose intolerance and subsequent ocular pathology in the fat sand rat. Sci Rep 14, 403 (2024).
Noa Rofe, Yuval Brosh, Hagar Vardi-Naim, et al. Salivary cortisol concentration and perceived stress measure in response to acute common stress: The role of morningness-eveningness preference. Authorea. February 10, 2023.
Mofaz, M., Yechezkel, M., Einat, H. et al. Real-time sensing of war’s effects on wellbeing with smartphones and smartwatches. Commun Med 3, 55 (2023).
Haim Einat, Vasia Kyrgiakou, Aikaterini Stravoravdi, Yelena Stukalin, Anat Lan & Konstantinos N. Fountoulakis (2023) Late chronotypes show lower scores on a combined measure of emotional wellbeing: a study in the general population in Greece, Biological Rhythm Research, 54:11, 732-742
Anat Lan, Tal Ron, Yelena Stukalin, Noga Kronfeld-Schor & Haim Einat (2023) Changes in menstrual cycle length and in sleep-wake behaviors during COVID-19 related lockdown in Israel, Health Care for Women International
Shi, Z.; Tuomilehto, J.; Kronfeld-Schor, N.; Alberti, G.; Stern, N.; El-Osta, A.; Chai, Z.; Bilu, C.; Einat, H.; Zimmet, P. The Circadian Syndrome Is a Significant and Stronger Predictor for Cardiovascular Disease than the Metabolic Syndrome—The NHANES Survey during 2005–2016. Nutrients 2022, 14, 5317.
Lan, A., Kotler, D., Kronfeld-Schor, N. et al. Changes in sleep patterns of college students in Israel during COVID-19 lockdown, a sleep diaries study. Sleep Biol. Rhythms 20, 309–314 (2022).
Kazavchinsky, L., Kara, N. Z. and Einat, H. (2022) 'Heterogeneity of lithium effects in the forced swim test, across more than within experiments', Acta Neuropsychiatrica,
Carmel Bilu, Tal Frolinger-Ashkenazi, Haim Einat, Paul Zimmet, Yulia Bishko, Dania Halperin, Noga Kronfeld-Schor, Effects of photoperiod and diet on BDNF daily rhythms in diurnal sand rats, Behavioural Brain Research, Volume 418, 2022
Bilu, C., Einat, H., Zimmet, P. et al. Beneficial effects of voluntary wheel running on activity rhythms, metabolic state, and affect in a diurnal model of circadian disruption. Sci Rep 12, 2434 (2022).
Bilu C, Kronfeld-Schor N, Zimmet P, Einat H. Day and night: A comment on "Neurobiological and behavioral mechanisms of circadian rhythm disruption in bipolar disorder: A critical multi-disciplinary literature review and agenda for future research from the ISBD task force on chronobiology". Bipolar Disord. 2022 Mar;24(2):211-212.
Bilu C, Einat H, Zimmet P, Vishnevskia-Dai V, Kronfeld-Schor N (2022) Beneficial effects of daytime high-intensity light exposure on daily rhythms, metabolic state and affect. Scientific Reports 10:19782
Oved Shay, Mofaz Merav, Lan Anat, Einat Haim, Kronfeld-Schor Noga, Yamin Dan and Shmueli Erez 2021Differential effects of COVID-19 lockdowns on well-being: interaction between age, gender and chronotypeJ. R. Soc. Interface.
Shi, Z, Tuomilehto, J, Kronfeld-Schor, N, Alberti, KG, Stern, N, El-Osta, A, Bilu, C, Einat, H, Zimmet, P (QU Health, Qatar University, Doha, Qatar; University of Helsinki, Helsinki, Finland; Tel Aviv University, Tel Aviv, Israel; College London, London, UK; Tel Aviv Medical Center, Tel Aviv, Israel; Monash University, Melbourne, Vic., Australia; The Chinese University of Hong Kong, Hong Kong SAR, China; Tel Aviv-Yaffo Academic College, Tel Aviv, Israel; Monash University, Melbourne, Vic., Australia). The circadian syndrome predicts cardiovascular disease better than metabolic syndrome in Chinese adults. J. Intern. Med. 2021; 289: 851– 860.
Lan A, Ron T, Oved S, et al. P.0518 Effects of COVID-19 lockdowns on well-being in subgroups of the population European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 2021 Dec;53:S382-S383. PMCID: PMC8716288.
Damri, O., Asslih, S., Shemesh, N. et al. Using mitochondrial respiration inhibitors to design a novel model of bipolar disorder-like phenotype with construct, face and predictive validity. Transl Psychiatry 11, 123 (2021).
Carmel Bilu, Noga Kronfeld-Schor, Paul Zimmet & Haim Einat (2021) Sex differences in the response to circadian disruption in diurnal sand rats, Chronobiology International
Stukalin Y, Lan A, Einat H (2020) Revisiting the validity of the mouse tail suspension test: Systematic review and meta-analysis of the effects of prototypic antidepressants. Neuroscience and Biobehavioral Reviews. 112:39-47
Lugasi, L.; Grinberg, I.; Sabag, R.; Madar, R.; Einat, H.; Margel, S. Proteinoid Nanocapsules as Drug Delivery System for Improving Antipsychotic Activity of Risperidone. Molecules 2020, 25, 4013.
Lugasi, L., Grinberg, I., Rudnick-Glick, S. et al. Designed proteinoid polymers and nanoparticles encapsulating risperidone for enhanced antipsychotic activity. J Nanobiotechnol 18, 149 (2020).
Langer E, Einat H, Stukalin Y (2020) Similarities and dissimilarities in the effects of benzodiazepines and specific serotonin reuptake inhibitors (SSRIs) in the defensive marbles burying test: a systematic review and meta-analysis. European Neuropsychopharmacology. 36: 38-49
Kazavchinsky L, Dahan S, Einat H (Nov 2020) Exploring test batteries for affective- and anxiety-like behaviors in female and male ICR and black Swiss mice. Acta Neuropsychiatrica. 32:293-302
Kara NZ, Flaisher-Grinberg S, Einat H (2020) Proposing the sweet solution preference test as a screening assay for anti-manic effects of mood stabilizers. Journal of Neuroscience Methods. 1;346:108920.
Bilu C, Zimmet P, Vishnevskia-Dai V, et al. Diurnality, Type 2 Diabetes, and Depressive-Like Behavior. Journal of Biological Rhythms. 2019;34(1):69-83.
Zimmet P, Alberti G, Stern N, Bilu C, El-Osta S, Einat H, Kronfeld-Schor N (2019) The Circadian Syndrome. Journal of Internal Medicine. 286:181-191
Yelena Stukalin, Haim Einat, Analyzing test batteries in animal models of psychopathology with multivariate analysis of variance (MANOVA): One possible approach to increase external validity, Pharmacology Biochemistry and Behavior, Volume 178, 2019, Pages 51-55
Wang J, Yun Q, Qian J, -J, Song H, -R, Wang L, Inkabi S, E, Xu R, -J, Hu Y, -M, Zhang W, -N, Einat H: Mice Lacking the Transcriptional Coactivator PGC-1α Exhibit Hyperactivity. Neuropsychobiology 2019;78:182-188.
Lydmila Kazavchinsky, Anat Dafna, Haim Einat, Individual variability in female and male mice in a test-retest protocol of the forced swim test, Journal of Pharmacological and Toxicological Methods, Volume 95, 2019, Pages 12-15
Carmel Bilu, Haim Einat, Katy Tal-Krivisky, Joseph Mizrahi, Vicktoria Vishnevskia-Dai, Galila Agam & Noga Kronfeld-Schor (2019) Red white and blue – bright light effects in a diurnal rodent model for seasonal affective disorder, Chronobiology International, 36:7, 919-926
Bilu, C., Einat, H., Barak, O. et al. Linking type 2 diabetes mellitus, cardiac hypertrophy and depression in a diurnal animal model. Sci Rep 9, 11865 (2019).
Anat Lan, Haim Einat, Questioning the predictive validity of the amphetamine-induced hyperactivity model for screening mood stabilizing drugs, Behavioural Brain Research, Volume 362, 2019, Pages 109-113

מענקים ופרסים | Grants and Awards

BSF

Autophagy and Depression

בשיתוף עם Prof. Anderson Grant University of Minnesota USA