פרופ' דבי שלו

Prof. Deborah Shalev

מוסד עיקרי

עזריאלי- מכללה אקדמית להנדסה ירושלים

Azrieli College of Engineering Jerusalem

טלפון

052-2227669

דוא״ל

debbie at jce.ac.il

דיסציפלינות ראשיותMain Disciplines

Chemistry, Medicinal Chemisty and Theranostics

דיסציפלינות משניותSecondary Disciplines

Drug Design and Development, Spectroscopy

תחומי מחקר / מילות מפתחKeywords

Nuclear magnetic resonance (NMR), Peptide-protein interactions, Peptides, Polymer systems, Structural analysis, Thermoanalytical methods

פרסומים ויצירות עיקריים / עדכנייםMain / Recent Publications

Penhasi, A., Baluashvili, I., Shalev, D. E.,An edible erodible semi-interpenetrating polymer network as a microcapsule shell to protect probiotic bacteria during reconstitution of powdered infant formula at elevated temperatures. J. Appl. Polym. Sci. 2022, e52201.
Shahar Rotem-Bamberger, Jamal Fahoum, Keren Keinan-Adamsky, Tomer Tsaban, Orly Avraham, Deborah E Shalev, Jordan H Chill, Ora Schueler-Furman (2022) Structural insights into the role of the WW2 domain on tandem WW–PPxY motif interactions of oxidoreductase WWOX. Journal of Biological Chemistry, 8
Shalev, D.E. Studying Peptide-Metal Ion Complex Structures by Solution-State NMR. Int. J. Mol. Sci. 2022, 23, 15957.
Alshanski, I., Shalev, D.E., Yitzchaik, S. et al. Determining the structure and binding mechanism of oxytocin-Cu2+ complex using paramagnetic relaxation enhancement NMR analysis. J Biol Inorg Chem 26, 809–815 (2021).
Mousa, R., Hidmi, T., Pomyalov, S. et al. Diselenide crosslinks for enhanced and simplified oxidative protein folding. Commun Chem 4, 30 (2021).
Adel Penhasi, Mila Gomberg, Deborah E. Shalev, A novel nicotine pectinate salt formulated in a specific time-controlled delivery system: A new approach for colon-targeted nicotine release, Journal of Drug Delivery Science and Technology, Volume 56, Part A, 2020
Nicotine pectinate salt formulated in a specific time-controlled delivery system: A new approach for colon-targeted nicotine release, Penhasi A, Gomberg M, Shalev DE, Journal of Drug Delivery Science and Technology 2020 56 (A)
Penhasi, A, Gertler, A, Baluashvili, I, Elzinaty, O, Shalev, DE. High modulus thermoplastic segmented polyurethane/poly(L-lactide) blends as potential candidates for structural implantable drug delivery systems: I. Structure-properties relationship study. J Appl Polym Sci. 2020; 137:e49517.
Samarasimhareddy, M., Shamir, M., Shalev, D. E., Hurevich, M., & Friedler, A. (2020). A Rapid and Efficient Building Block Approach for Click Cyclization of Peptoids. Frontiers in chemistry, 8, 405.
Talhami, A., Swed, A., Hess, S., Ovadia, O., Greenberg, S., Schumacher-Klinger, A., Rosenthal, D., Shalev, D. E., Hurevich, M., Lazarovici, P., Hoffman, A., & Gilon, C. (2020). Cyclizing Painkillers: Development of Backbone-Cyclic TAPS Analogs. Frontiers in chemistry, 8, 532577.
Tayri-Wilk, T., Slavin, M., Zamel, J. et al. Mass spectrometry reveals the chemistry of formaldehyde cross-linking in structured proteins. Nat Commun 11, 3128 (2020).
O. Weil-Ktorza, N. Rege, S. Lansky, D. E. Shalev, G. Shoham, M. A. Weiss, N. Metanis, Chem. Eur. J. 2019, 25, 8513.
Tailoring the self-assembly of a tripeptide for the formation of antimicrobial surfaces. Nir S, Zanuy D, Zada T, Agazani O, Aleman C, Shalev DE, Reches M. Nanoscale 2019, 11, 8752-8759
The Bacterial Extracellular Matrix Protein TapA Is a Two-Domain Partially Disordered Protein. Abbasi R, Mousa R, Dekel N, Amartely H, Danieli T, Lebendiker M, Levi-Kalisman Y, Shalev DE, Metanis N, Chai L. Chembiochem. 2019, 20, 355-359
Michal S. Shoshan, Noa Dekel, Wojciech Goch, Deborah E. Shalev, Tsafi Danieli, Mario Lebendiker, Wojciech Bal, Edit Y. Tshuva, Unbound position II in MXCXXC metallochaperone model peptides impacts metal binding mode and reactivity: Distinct similarities to whole proteins, Journal of Inorganic Biochemistry, Volume 159, 2016, Pages 29-36