ד"ר איימן אבו עמאר

Dr. Aiman Abu Ammar

מוסד עיקרי

עזריאלי- מכללה אקדמית להנדסה ירושלים

Azrieli College of Engineering Jerusalem

טלפון

02-6591835

דוא״ל

aimanab@jce.ac.il

דיסציפלינות ראשיותMain Disciplines

Medicinal Chemisty and Theranostics, Medicine - Biomedical Engineering, Medicine - Cancer and Oncology, Nanotechnology, Pharmaceutical Science

דיסציפלינות משניותSecondary Disciplines

Drug Design and Development

תחומי מחקר / מילות מפתחKeywords

Biodegradable polymers, Biomimicry, Cancer therapy, Controlled drug release, Drug delivery, Lipophilic drugs, Microneedles, Nanoparticles, Steroids

פרסומים ויצירות עיקריים / עדכנייםMain / Recent Publications

Dawud, H., Edelstein-Pardo, N., Mulamukkil, K., Amir, R.J., Abu Ammar, A., 2024. Hydrogel Microneedles with Programmed Mesophase Transitions for Controlled Drug Delivery. ACS Applied Bio Materials
Bader, N., Abu Ammar, A., 2024. Incorporating surfactants into PCL microneedles for sustained release of a hydrophilic model drug. International Journal of Pharmaceutics, 652,123826.
Laura B. Kerrigan, Sarah A. Stewart, Juan Domínguez-Robles, Aaron J. Brady, Aiman Abu Ammar, Ryan F. Donnelly, Andi Dian Permana, Eneko Larrañeta,
Drug delivery systems for thyroid disease treatment: A mini review on current therapies and alternative approaches, Journal of Drug Delivery Science and Technology, Volume 87, 2023, 104861
Fragassi, A., Greco, A., Di Francesco, M., Ceseracciu, L., Abu Ammar, A., Dvir, I., Lee Moore, T., Kasem, H. and Decuzzi, P. , 2023. Tribological behavior of shape-specific microplate-enriched synovial fluid on a linear two-axis tribometer. Friction, 12(3), pp.539-553.
Dawud, H.; Abu Ammar, A. Rapidly Dissolving Microneedles for the Delivery of Steroid-Loaded Nanoparticles Intended for the Treatment of Inflammatory Skin Diseases. Pharmaceutics 2023, 15, 526.
David Badler, Yuri Kligerman, Aiman Abu Ammar, Haytam Kasem, On the integration of micro textures of different shapes for the stability of biomimetic attachment systems, Biotribology,
Volumes 33–34, 2023, 100234
David Badler, Roman Goltsberg, Aiman Abu Ammar, Haytam Kasem, Experimental study of adhesion, friction, and peeling of biomimetic combined micro-mushroom and micro-spatulae textures, Tribology International, Volume 186, 2023, 108609
Abu-Much, A., Darawshi, R., Dawud, H., Kasem, H., Abu Ammar, A., 2022. Preparation and characterization of flexible furosemide-loaded biodegradable microneedles for intradermal drug delivery. Biomater. Sci., 2022,10, 6486-6499
Muhammad Abdel-Haq, Rayan Alyan, Kareem Abd-Rbo, Haytam Kasem, Aiman Abu Ammar, Biomimetic clotrimazole-loaded PLGA films with enhanced adhesiveness for controlled drug release, International Journal of Pharmaceutics, Volume 601, 2021
Nikhil Biswas, Aiman Abu Ammar, Marina Frušić-Zlotkin, Naama Adi-Hen, Yonat Lehman-Katabi, Yael Levi-Kalisman, Taher Nassar, Simon Benita, Biodistribution and efficacy of the anticancer drug, oxaliplatin palmitate acetate, in mice, International Journal of Pharmaceutics, Volume 604, 2021
Jahshan, F., Abu Ammar, A., Ertracht, O., Eisenbach, N., Daoud, A., Sela, E., Atar, S., Zussman, E., Fichtman, B., Harel, A. and Gruber, M., 2021. Local Delivery of Mometasone Furoate from an Eluting Endotracheal Tube Reduces Airway Morbidity Following Long-Term Animal Intubation. ACS Applied Bio Materials, 4(5), pp.4131-4139.
Aiman Abu Ammar, Muhammad Abdel-Haq, Kareem Abd-Rbo, Haytam Kasem, Developing Novel Poly(Lactic-Co-Glycolic Acid) (PLGA) Films with Enhanced Adhesion Capacity by Biomimetic Mushroom-Shaped Microstructures, Biotribology, Volume 27, 2021
Ahmad Kabha, Alexandra Bukchin-Tihomirov, Idan Shlomi, Aiman Abu Ammar, Miri Bidder, Gilad Amiel, and Eyal Zussman. Biodegradable Controlled-Release Device for Localized Chemotherapeutic Treatment of Bladder Cancer. ACS Biomater. Sci. Eng. 2021, 7, 6, 2548–2557
Jahshan, F., Ertracht, O., Eisenbach, N., Daoud, A., Sela, E., Atar, S., Abu Ammar, A. and Gruber, M., 2020. A novel rat model for tracheal mucosal damage assessment of following long term intubation. International journal of pediatric otorhinolaryngology, 128, pp.109738.
Far, J., Abdel-Haq, M., Gruber, M. and Abu Ammar, A., 2020. Developing biodegradable nanoparticles loaded with mometasone furoate for potential nasal drug delivery. ACS Omega, 5 (13), pp.7432-7439.
Abu Ammar, A., Nasereddin, A., Ereqat, S., Dan-Goor, M., Jaffe, C.L., Zussman, E. and Abdeen, Z., 2019. Amphotericin B-loaded nanoparticles for local treatment of cutaneous leishmaniasis. Drug delivery and translational research, 9(1), pp.76-84.
Jahshan, F., Ertracht, O., Abu Ammar, A., Ronen, O., Srouji, S., Apel-Sarid, L., Eisenbach, N., Atar, S., Sela, E. and Gruber, M., 2018. A novel rat model for assessment of laryngotracheal injury following transoral intubation. International journal of pediatric otorhinolaryngology, 113, pp.4-10.
Abu Ammar, A., Gruber, M., Martin, P., Stern, O., Jahshan, F., Ertracht, O., Sela, E., Srouji, S. and Zussman, E., 2018. Local delivery of mometasone furoate from an eluting endotracheal tube. Journal of Controlled Release, 272, pp.54-61.
Khamaysi, I., Abu Ammar, A., Vasilyev, G., Arinstein, A., Chowers, Y. and Zussman, E., 2017. Differentiation of pancreatic cyst types by analysis of rheological behavior of pancreatic cyst fluid. Scientific reports, 7(1), pp.1-8.
Lancuški, A., Abu Ammar, A., Avrahami, R., Vilensky, R., Vasilyev, G. and Zussman, E., 2017. Design of starch-formate compound fibers as encapsulation platform for biotherapeutics. Carbohydrate polymers, 158, pp.68-76.
Abu Ammar, A., Raveendran, R., Gibson, D., Nassar, T. and Benita, S., 2016. A lipophilic Pt (IV) oxaliplatin derivative enhances antitumor activity. Journal of medicinal chemistry, 59(19), pp.9035-9046.