פרופ' אביב שיש

Rachel Twitto-Greenberg, Sigal Liraz-Zaltsman, Daniel M. Michaelson, Ori Liraz, Irit Lubitz, Dana Atrakchi-Baranes, Chen Shemesh, Uri Ashery, Itzik Cooper, Ayelet Harari, Dror Harats, Michal Schnaider-Beeri, Aviv Shaish, 9-cis beta-carotene-enriched diet significantly improved cognition and decreased Alzheimer’s disease neuropathology and neuroinflammation in Alzheimer’s disease-like mouse models, Neurobiology of Aging, Volume 133, 2024, Pages 16-27

Tal Almog, Rom Keshet, Michal Kandel-Kfir, Aviv Shaish, Ron N Apte, Dror Harats, Yehuda Kamari, Gene deletion of Interleukin-1α reduces ER stress-induced CHOP expression in macrophages and attenuates the progression of atherosclerosis in apoE-deficient mice, Cytokine, Volume 167, 2023, 156212

Melnikov, N., Kamari, Y., Kandel-Kfir, M., Barshack, I., Ben-Amotz, A., Harats, D., Shaish, A., et al. (2022). β-Carotene from the Alga Dunaliella bardawil Decreases Gene Expression of Adipose Tissue Macrophage Recruitment Markers and Plasma Lipid Concentrations in Mice Fed a High-Fat Diet. Marine Drugs, 20(7), 433. MDPI AG.

Cohen H, Hassin-Baer S and Shaish A (2022) Features of the metabolic syndrome and subclinical atherosclerosis in patients with cerebrotendinous xanthomatosis: An augmented risk for premature cardiovascular disease. Front. Genet. 13:997069

A. Leikin-Frenkel, H. Cohen, R. Keshet, R. Shnerb-GanOr, M. Kandel-Kfir, A. Harari, K.S. Hollander, A. Shaish, D. Harats, Y. Kamari, The effect of α-linolenic acid enrichment in perinatal diets in preventing high fat diet-induced SCD1 increased activity and lipid disarray in adult offspring of low density lipoprotein receptor knockout (LDLRKO) mice, Prostaglandins, Leukotrienes and Essential Fatty Acids, Volume 184, 2022, 102475

Shahar Delman, Mika Anekstein, Arnon Afek, Rachel Twitto-Greenberg, Dror Harats, Reut Shnerb Ganor, Ayelet Harari & Aviv Shaish (2021) 9-cis and all-trans beta-carotene isomers of super critical CO2-extracted Dunaliella oil are absorbed and accumulated in mouse tissues, Applied Phycology, 2:1, 74-79

Alicia Leikin-Frenkel, Sigal Liraz-Zaltsman, Kenneth S. Hollander, Dana Atrakchi, Orly Ravid, Daniel Rand, Michal Kandel-Kfir, Hila Israelov, Hofit Cohen, Yehuda Kamari, Aviv Shaish, Dror Harats, Michal Schnaider-Beeri, Itzik Cooper, Dietary alpha linolenic acid in pregnant mice and during weaning increases brain docosahexaenoic acid and improves recognition memory in the offspring, The Journal of Nutritional Biochemistry, Volume 91, 2021

Alicia Leikin-Frenkel, Aya Mohr–Sasson, Matan Anteby, Michal Kandel-Kfir, Ayelet Harari, Roni Rahav, Yehuda Kamari, Aviv Shaish, Dror Harats, Hofit Cohen, Israel Hendler, Blood fatty acid analysis reveals similar n-3 fatty acid composition in non-pregnant and pregnant women and their neonates in an Israeli pilot study, Prostaglandins, Leukotrienes and Essential Fatty Acids, Volume 173, 2021

Michal Kandel-Kfir, Rolando Garcia-Milan, Itai Gueta, Irit Lubitz, Ilan Ben-Zvi, Aviv Shaish, Lidar Shir, Dror Harats, Milind Mahajan, Allon Canaan and Yehuda Kamari (2020) IFNg potentiates TNFa/TNFR1 signaling to induce FAT10 expression in macrophages. Molecular Immunology 117:101-109.

Maya Sultan, Dikla Ben-Shushan, Michael Peled, Yehuda Kamari, Shuli Isman, Iris Barshack, Ralf-Jürgen Kuban, Hartmut Kühn, Dror Harats, and Aviv Shaish*. (2020) Specific overexpression of 15-lipoxygenase in endothelial cells promotes cancer cell death in an in vivo Lewis lung carcinoma mouse model. Advances in Medical Sciences, 65(1):111-119.

Ayelet Harari, Nir Melnikov, Dror Harats, Ami Ben-Amotz, Michal Kandel Kfir, Yehuda Kamari, Lidor Mahler, Aviv Shaish (2020). Dietary β‐Carotene Rescues Vitamin A Deficiency and Inhibits Atherogenesis in Apolipoprotein E‐Deficient Mice. Nutrients, 12, 1625.

Ayelet Harari, Adelle CF Coster, Arthur Jenkins, Aimin Xu, Jerry R, Greenfield, Dror Harats, Aviv Shaish*, Dorit Samocha-Bonet* (2020) Obesity and insulin resistance are inversely associated with serum and adipose tissue carotenoid concentrations in adults (* equal contribution) J of Nutrition. 150:38-46.

A. Harari, A. Leikin Frenkel, A. Sagee, H. Cohen, Y. Kamari, Kandel Kfir M., D. Harats, A. Shaish. (2020) Addition of Fish oil to Atherogenic High Fat Diet Inhibited Atherogenesis while Olive Oil did not, in LDL Receptor KO Mice. Nutrition, Metabolism and Cardiovascular Disease, 12;30(4):709-716.

Tal Almog, Michal Kandel-Kfir, Aviv Shaish, Hana Levkovich, Gadi Shlomai, Iris Barshack, Rinke Stienstra, Yaniv Lustig, Alicia Leikin-Frenkel, Ayelet Harari,Yoram Bojanover , Ron N. Apte, Dror Harats, Yehuda Kamari. (2019). Interleukin-1alpha Deficiency Reduces Adiposity, Glucose Intolerance and Hepatic De-novo Lipogenesis in Diet-induced Obese Mice. Diabetes Research and Care 17;7(1).

Lidor Mahler, Ayelet Harari, Dror Harats, Ami Ben-Amotz, Michael Peled, Alicia Leikin-Frenkel, Michal Kandel Kfir, Yehuda Kamari, Aviv Shaish (2019) Combined Treatment with 9-cis β-Carotene and 22R-hydroxycholesterol Augments Cholesterol Efflux in Macrophages. Algal Research. Volume 44.

Victoria Edelshtain, Alon Peled, Adi Tzameret, Sarah Pri Chen, Hana Ziv, Estela Derazne, Dror Harats, Rachel Greenberg, Ayelet Harari, Aviv Shaish, Ifat Sher, Ygal Rotenstreich (2019) Long-term treatment with 9-cis-β-carotene rich alga Dunaliella bardawil ameliorates photoreceptor degeneration in a mouse model of retinoid cycle defect. Algal Research. Volume 43.

Elhaik Goldman S, Goez D, Last D, Naor S, Liraz Zaltsman S, Sharvit-Ginon I, AtrakchiBaranes D, Shemesh C, Twitto-Greenberg R, Tsach S, Lotan R, Leikin-Frenkel A, Shish A, Mardor Y, Schnaider Beeri M, Cooper I. High-fat diet protects the blood-brain barrier in an Alzheimer's disease mouse model. (2018) Aging Cell. 2018 Aug 6:e12818.

Reut Shnerb Ganor, Dror Harats, Ginette Schiby, Kinneret Rosenblatt, Irit Lubitz, *Aviv
Shaish, *Ophira Salomon (2018) Elderly apolipoprotein E -/- mice with advanced
atherosclerotic lesions in the aorta do not develop Alzheimer's disease-like pathologies. Molecular Medicine Reports, 17(2):2488-2492 (*Equal contribution)

Shiri Uri-Belapolsky, Lihi Ninio-Many, Aviv Shaish, Mattan Levi, Dror Harats, Irit Miller,
Yehuda Kamari, Ruth Shalgi (2017) Interleukin 1-alpha deficiency increases the expression of follicle stimulating hormone receptors in granulosa cells. Molecular Reproduction and Development, 84(6):460-467.